The Endocannabinoid System

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The Endocannabinoid System: Why CBD is Effective

The endocannabinoid system is a biochemical communicative network that is found within all major systems in the human body. Endocannabinoid systems are actually found within all mammals, fish, reptiles, amphibians, and birds. This complex system of lipid-based retrograde neurotransmitters is responsible for regulating vital functions throughout our physiology. The recent discovery of the endocannabinoid system has changed our understanding of brain chemistry as well as healing properties among human biology.


Mechoulam, the scientist who discovered the endocannabinoid system, has stated that his cannabis research is solely responsible for finding this new physiological system that has immense importance. By studying how and why our physiology reacts to cannabis, we were able to discover cannabinoid receptors as well as endocannabinoids.  

Endocannabinoids and Cannabinoid Receptors

Endocannabinoids are cannabinoids that are naturally-occurring within our own bodies. CBD along with the other numerous cannabinoids, like THC, CBN, etc., are phytocannabinoids, meaning they’re naturally-occurring in plants. CBD has the same chemical properties as the endocannabinoids found in our own bodies, that is why it is so effective for such a wide-ranging scope of conditions.


The endocannabinoid system has countless cannabinoid receptors that are found throughout the brain, immune system, peripheral nervous system, skin, gut, spleen, heart, bones, liver, kidneys, blood vessels, endocrine glands, reproductive organs, and lymph cells. Scientists have been able to identify two of these cannabinoid receptors as CB1 and CB2 receptors.

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What Your Endocannabinoid System Regulates

Through extensive research, scientists have found that cannibinoid receptor signaling actually regulates inflammation, pain, appetite, analgesia, gastrointestinal mobility, immune cells, hormones, sleep cycles, and mood-altering neurotransmitters. The endocannabinoid system is responsible for regulating all physiological and cognitive processes, every element that makes up our day-to-day experience. The endocannabinoid system is also responsible for fertility and reproductive processes.

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Clinical Endocannabinoid Deficiency: Why CBD Works

Scientists have now concluded that clinical endocannabinoid deficiency is responsible for a wide range of chronic conditions including migraines and many more. Endocannabinoid deficiency can be caused by poor diet, lack of exercise, environmental toxins, as well as genetic predispositions. While clinical endocannabinoid deficiency is not the sole cause of these conditions, those suffering from deficiency can find viable treatment through consistent cannabinoid therapy.